Phencyclidine
Phencyclidine
Phencyclidine (pronounced: fen-si-kli-deen), often abbreviated as PCP, is a psychoactive drug that was originally developed in the 1950s as a surgical anesthetic. Its use in humans was discontinued due to its side effects, which include hallucinations, mania, delirium, and disorientation.
Etymology
The term "Phencyclidine" is derived from the chemical name phenylcyclohexylpiperidine. It is often referred to by its street names such as "Angel Dust", "Hog", and "Rocket Fuel".
Pharmacology
Phencyclidine is classified as a dissociative anesthetic, meaning it distorts perceptions of sight and sound and produces feelings of detachment from the environment and self. It primarily acts as an NMDA receptor antagonist, which blocks the activity of the NMDA receptor and produces effects similar to those of ketamine and dextromethorphan.
Effects
The effects of Phencyclidine can vary greatly depending on the dose, but they generally include hallucinations, distorted perceptions of sounds, and violent behavior. At high doses, it can cause seizures, coma, and death. Long-term use can lead to memory loss, difficulties with speech and thinking, depression, and weight loss.
Related Terms
- Psychoactive drug
- Anesthetic
- Dissociative anesthetic
- NMDA receptor antagonist
- Ketamine
- Dextromethorphan
External links
- Medical encyclopedia article on Phencyclidine
- Wikipedia's article - Phencyclidine
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