Persistent adrenarche syndrome

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Persistent adrenarche syndrome

Persistent adrenarche syndrome (PAS, /pərˈsɪstənt ædrɪˈnɑːrki sɪnˈdroʊm/), also known as premature adrenarche, is a medical condition characterized by the early onset of adrenarche in children. The term "adrenarche" refers to the maturation of the adrenal gland, which typically occurs between the ages of 6 and 8. In children with PAS, this process begins prematurely, often leading to the early development of secondary sexual characteristics.

Etymology

The term "Persistent adrenarche syndrome" is derived from the words "persistent", meaning continuing without change, "adrenarche", referring to the maturation of the adrenal glands, and "syndrome", a term used to describe a group of symptoms that consistently occur together.

Symptoms

Symptoms of PAS may include early pubic hair growth, body odor, and accelerated growth and bone maturation. These symptoms are caused by an increase in the production of androgens by the adrenal glands.

Diagnosis

Diagnosis of PAS is typically based on physical examination, medical history, and laboratory tests to measure levels of adrenal hormones. It is important to differentiate PAS from other conditions that can cause early puberty, such as congenital adrenal hyperplasia and Cushing's syndrome.

Treatment

Treatment for PAS is usually not necessary unless the child is experiencing distress or complications. In some cases, medication may be used to slow down the rate of growth and development.

Related Terms

External links

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