Pateclizumab

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Pateclizumab

Pateclizumab (pronounced: puh-teh-cli-zoo-mab) is a monoclonal antibody designed for the treatment of rheumatoid arthritis and other autoimmune diseases.

Etymology

The name "Pateclizumab" is derived from the International Nonproprietary Naming system for pharmaceutical substances. The "-mab" suffix indicates that it is a monoclonal antibody, while the prefix "Patecli-" is unique to this specific drug.

Usage

Pateclizumab is used in the treatment of rheumatoid arthritis, a chronic inflammatory disorder affecting many joints, including those in the hands and feet. It is also being studied for use in other autoimmune diseases, where the body's immune system mistakenly attacks the body's own cells.

Mechanism of Action

Pateclizumab works by targeting and inhibiting the lymphocyte function-associated antigen 1 (LFA-1), a protein involved in the movement of leukocytes (white blood cells) and their binding to other cells. By blocking LFA-1, Pateclizumab can reduce inflammation and slow the progression of autoimmune diseases.

Related Terms

  • Monoclonal Antibody: A type of protein made in the laboratory that can bind to substances in the body, including cancer cells.
  • Rheumatoid Arthritis: A chronic inflammatory disorder affecting many joints, including those in the hands and feet.
  • Autoimmune Diseases: Conditions in which your immune system mistakenly attacks your body.
  • Lymphocyte: A type of white blood cell that is part of the immune system.
  • LFA-1: A protein involved in the movement of leukocytes (white blood cells) and their binding to other cells.

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