Paromomycin sulfate
Paromomycin Sulfate
Paromomycin sulfate (pronunciation: par-oh-moe-MYE-sin sul-fate) is an aminoglycoside antibiotic used to treat certain parasitic infections. It is also known as Humatin and Paromycin.
Etymology
The term "Paromomycin" is derived from the Greek words "para" meaning "against" and "momo" meaning "single". The "mycin" suffix is common in antibiotics and is derived from the Greek "mykes" meaning "fungus". The "sulfate" refers to the salt form of the drug, which enhances its solubility and stability.
Usage
Paromomycin sulfate is primarily used to treat intestinal amebiasis, a parasitic infection of the intestines caused by the amoeba Entamoeba histolytica. It is also used in the treatment of hepatic coma or hepatic encephalopathy, a condition that occurs when the liver is unable to remove toxins from the blood.
Mechanism of Action
Paromomycin sulfate works by binding to the ribosomal RNA of the parasite, inhibiting protein synthesis and leading to the death of the parasite.
Side Effects
Common side effects of Paromomycin sulfate include nausea, abdominal cramps, and diarrhea. Severe side effects may include allergic reactions, hearing loss, and kidney damage.
Related Terms
- Aminoglycoside
- Antibiotic
- Intestinal amebiasis
- Entamoeba histolytica
- Hepatic coma
- Hepatic encephalopathy
- Ribosomal RNA
External links
- Medical encyclopedia article on Paromomycin sulfate
- Wikipedia's article - Paromomycin sulfate
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