Pityriasis lichenoides et varioliformis acuta
Pityriasis Lichenoides et Varioliformis Acuta
Pityriasis Lichenoides et Varioliformis Acuta (PLEVA) (pronounced: pit-ih-rye-uh-sis lie-kuh-noy-deez et vair-ee-oh-li-form-is ah-kyoo-ta) is a rare dermatological condition characterized by the sudden onset of small, red, scaling papules that may evolve into necrotic ulcers. The etymology of the term is derived from the Greek words 'pityron' meaning bran, 'lichen' meaning tree moss, and 'varioliformis' meaning resembling smallpox.
Symptoms
The primary symptom of PLEVA is the appearance of small, red, scaling papules that may evolve into necrotic ulcers. These lesions typically appear on the trunk and limbs, but can also occur on the face and scalp. Other symptoms may include fever, malaise, and itching.
Causes
The exact cause of PLEVA is unknown, but it is thought to be an abnormal immune response to an unknown antigen. Some researchers believe that it may be triggered by a viral or bacterial infection.
Diagnosis
Diagnosis of PLEVA is typically based on the characteristic appearance of the skin lesions and confirmed by a skin biopsy. Other tests may be performed to rule out similar conditions such as lymphoma or psoriasis.
Treatment
Treatment for PLEVA is aimed at managing symptoms and may include topical corticosteroids, light therapy, and oral antibiotics. In severe cases, systemic therapies such as methotrexate or acitretin may be used.
Prognosis
The prognosis for PLEVA is generally good, but the condition can be chronic and relapsing. Most patients experience a complete resolution of symptoms within a few months to a few years.
See Also
External links
- Medical encyclopedia article on Pityriasis lichenoides et varioliformis acuta
- Wikipedia's article - Pityriasis lichenoides et varioliformis acuta
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