Paraneoplastic keratoderma
Paraneoplastic Keratoderma
Paraneoplastic keratoderma (pronunciation: para-neo-plastic ker-a-to-der-ma) is a rare skin condition that is associated with internal malignancies.
Etymology
The term "paraneoplastic" is derived from the Greek words "para" meaning "beside" and "neoplasia" meaning "new growth", referring to the condition's association with cancerous growths. "Keratoderma" comes from the Greek "keras" meaning "horn" and "derma" meaning "skin", referring to the thickening and hardening of the skin that characterizes this condition.
Definition
Paraneoplastic keratoderma is a cutaneous manifestation that is associated with internal malignancies, particularly gastrointestinal cancer and lung cancer. It is characterized by the thickening and hardening of the skin, particularly on the palms of the hands and soles of the feet.
Symptoms
Symptoms of paraneoplastic keratoderma may include:
- Thickening and hardening of the skin
- Redness and scaling
- Pain and tenderness
- Cracks or fissures in the skin
Diagnosis
Diagnosis of paraneoplastic keratoderma is typically made based on the clinical presentation and the presence of an associated internal malignancy. Skin biopsy may be performed to confirm the diagnosis.
Treatment
Treatment of paraneoplastic keratoderma primarily involves treating the underlying malignancy. Topical treatments may be used to manage the skin symptoms.
Related Terms
External links
- Medical encyclopedia article on Paraneoplastic keratoderma
- Wikipedia's article - Paraneoplastic keratoderma
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