PAH clearance
PAH Clearance
PAH clearance (pronounced: P-A-H clearance) is a medical term used to describe the process by which the kidneys remove Para-Aminohippuric Acid (PAH) from the bloodstream.
Etymology
The term "PAH clearance" is derived from the name of the substance that is being cleared, Para-Aminohippuric Acid, and the medical term "clearance", which refers to the removal of a substance from the body.
Definition
PAH clearance is a measure of the renal plasma flow, or the amount of blood that is filtered by the kidneys per unit of time. It is used in medical and physiological research to assess the function of the kidneys and their ability to filter and remove waste products from the bloodstream.
Process
The process of PAH clearance involves the filtration of blood through the kidneys, where PAH is removed and excreted in the urine. This process is used as a measure of the effective renal plasma flow (ERPF), which is the volume of plasma from which a substance has been completely removed (cleared) by the kidneys in a given time period.
Related Terms
- Renal Plasma Flow - The volume of blood that is filtered by the kidneys per unit of time.
- Para-Aminohippuric Acid - A substance that is used to measure renal plasma flow and PAH clearance.
- Effective Renal Plasma Flow (ERPF) - The volume of plasma from which a substance has been completely removed (cleared) by the kidneys in a given time period.
- Glomerular Filtration Rate (GFR) - The rate at which the kidneys filter blood, measured in milliliters per minute.
External links
- Medical encyclopedia article on PAH clearance
- Wikipedia's article - PAH clearance
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