Osteoid

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Osteoid

Osteoid (/ɒˈstiːɔɪd/; from the Greek 'osteon', meaning bone, and 'eidos', meaning form or shape) is the unmineralized, organic portion of the bone matrix that forms prior to the maturation of bone tissue. It is produced by osteoblasts, and eventually mineralizes to form mature bone tissue.

Etymology

The term 'osteoid' is derived from the Greek words 'osteon', which means bone, and 'eidos', which means form or shape. This reflects the role of osteoid as the initial framework that gives shape to bone during the process of bone formation.

Structure

Osteoid is primarily composed of collagen, specifically type I collagen, and ground substance. The ground substance is rich in glycosaminoglycans (GAGs), proteoglycans, and glycoproteins. These components provide the osteoid with its characteristic flexibility and resilience.

Function

The primary function of osteoid is to serve as a framework for the deposition of calcium and phosphate ions, which will eventually mineralize to form mature bone tissue. This process is known as ossification. Osteoid also plays a crucial role in the repair of fractures and the remodeling of bone.

Related Terms

  • Osteoblast: A type of cell that is responsible for the formation of osteoid.
  • Ossification: The process by which osteoid mineralizes to form mature bone tissue.
  • Osteocyte: A cell that is derived from osteoblasts and is embedded within the fully formed bone tissue.
  • Osteoclast: A type of cell that breaks down bone tissue, allowing for the remodeling and repair of bones.

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