Osler's node

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Osler's Node

Osler's Node (pronounced: OZ-lerz node) is a medical term referring to a specific symptom often associated with certain types of infective endocarditis.

Etymology

The term is named after Sir William Osler, a Canadian physician and one of the founding professors at Johns Hopkins Hospital. He first described the condition in the late 19th century.

Definition

Osler's nodes are painful, red, raised lesions found on the hands and feet. They are typically small, measuring between 1 to 2 cm in diameter. These nodes are caused by the deposition of immune complexes and are indicative of a systemic immune response.

Related Terms

  • Infective Endocarditis: An infection of the inner lining of the heart chambers and valves.
  • Janeway Lesions: Painless, small, flat, red or purple spots on the palms and soles. They are also associated with infective endocarditis.
  • Roth's Spots: Retinal hemorrhages with white or pale centers, another possible sign of infective endocarditis.
  • Immune Complex: A combination of an antibody and an antigen, often forming in response to infection.

See Also

External links

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