Nuclear atypia
Nuclear Atypia
Nuclear atypia (pronounced: noo-klee-er a-tip-ee-a) is a term used in pathology to describe abnormal cell nuclei. It is often associated with malignancy and is a key feature in the diagnosis of cancer.
Etymology
The term "nuclear atypia" is derived from the Greek words "nucleus" meaning kernel or seed, and "atypia" meaning not typical. It was first used in medical literature in the late 19th century.
Definition
Nuclear atypia refers to the abnormal appearance of a cell's nucleus under a microscope. This can include changes in size (nuclear enlargement), shape (nuclear irregularity), and staining characteristics (hyperchromasia). These changes are often indicative of abnormal cell growth or neoplasia.
Related Terms
- Hyperchromasia: An increase in the staining intensity of the cell nucleus, often seen in nuclear atypia.
- Neoplasia: The process of abnormal and uncontrolled cell growth, often leading to the formation of a tumor.
- Malignancy: A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Malignant cells can also spread to other parts of the body through the blood and lymph systems.
- Pathology: The scientific study of disease processes; it involves the examination of tissues, cells, and bodily fluids in order to make a diagnosis of disease.
See Also
External links
- Medical encyclopedia article on Nuclear atypia
- Wikipedia's article - Nuclear atypia
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