Norgestrel
Norgestrel (pronounced: nor-JES-trel) is a synthetic progestogen used in various forms of hormonal contraception. It is a racemic mixture of two stereoisomers, levonorgestrel and dextronorgestrel, in equal proportions.
Etymology
The term "Norgestrel" is derived from nor- (a prefix used in organic chemistry to denote a structural relation to a parent compound by the removal of one carbon atom) and gestrel (a suffix used in medicine to denote a synthetic progestogen).
Pharmacology
Norgestrel is a progestogen that is used in hormonal contraception. It is a synthetic form of the naturally occurring hormone progesterone. Norgestrel works by preventing ovulation, altering the cervical mucus to make it difficult for sperm to reach the egg, and changing the lining of the uterus to prevent a fertilized egg from implanting.
Uses
Norgestrel is used in several different types of hormonal contraception, including combined oral contraceptive pills, progestogen-only pills, and intrauterine systems. It is also used in hormone replacement therapy for menopausal symptoms.
Side Effects
Common side effects of Norgestrel include nausea, vomiting, headache, bloating, breast tenderness, swelling of the ankles/feet (fluid retention), or weight change may occur.
Related Terms
- Levonorgestrel: The active form of Norgestrel used in many hormonal contraceptives.
- Dextronorgestrel: The inactive form of Norgestrel.
- Progestogen: A type of hormone that Norgestrel mimics.
- Hormonal Contraception: The use of hormones to prevent pregnancy, which Norgestrel is used for.
External links
- Medical encyclopedia article on Norgestrel
- Wikipedia's article - Norgestrel
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