Nitrofuran

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Nitrofuran

Nitrofuran (pronunciation: /ˈnaɪtrəˌfjʊərən/) is a class of antibacterial drugs that are characterized by a nitrofuran functional group.

Etymology

The term "Nitrofuran" is derived from two words: "nitro" referring to the nitro group (NO2) and "furan" referring to the furan ring structure present in these compounds.

Usage

Nitrofurans are primarily used in the treatment of urinary tract infections (UTIs). They work by inhibiting bacterial DNA synthesis, thereby preventing the bacteria from reproducing and spreading. The most commonly used nitrofuran is Nitrofurantoin, which is specifically indicated for the treatment of UTIs caused by Escherichia coli or Staphylococcus saprophyticus.

Related Terms

  • Nitrofurantoin: A type of nitrofuran used to treat urinary tract infections.
  • Furan: A heterocyclic organic compound that forms the basis of the nitrofuran structure.
  • Antibacterial: Substances that inhibit the growth or kill bacteria.
  • Urinary tract infections: Infections that occur in any part of the urinary system.

Side Effects

Like all medications, nitrofurans can cause side effects. Common side effects include nausea, vomiting, and diarrhea. In rare cases, nitrofurans can cause serious lung, liver, or nerve problems.

Precautions

Nitrofurans should not be used in people with a history of severe allergic reactions to them. They should also be used with caution in people with kidney disease, as the drugs are primarily excreted through the kidneys.

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