Neurulation

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Neurulation (pronounced: noor-yuh-LAY-shun) is a fundamental process in early embryonic development, where the neural tube is formed. This process is crucial for the proper formation of the central nervous system (CNS).

Etymology

The term "neurulation" is derived from the Greek word "neuron" meaning nerve, and the Latin suffix "-ation" meaning action or process.

Process

Neurulation begins when the neural plate, a flat group of cells, transforms into a tube-like structure called the neural tube. This transformation occurs through a series of complex morphological changes, primarily folding and bending of the neural plate.

The process of neurulation can be divided into two main stages: primary neurulation and secondary neurulation.

  • Primary neurulation involves the formation of the neural tube from the neural plate. This process gives rise to the brain and the spinal cord.
  • Secondary neurulation involves the formation of the lower part of the spinal cord. This process occurs after primary neurulation and involves the aggregation and condensation of mesenchymal cells into a solid rod, which then hollows out to form the neural tube.

Related Terms

See Also

References

  • Gilbert, S.F. (2000). Developmental Biology. 6th Edition. Sinauer Associates, Inc. Sunderland (MA).

External links

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