Multi-organ failure

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Multi-organ failure

Multi-organ failure (pronunciation: /ˈmʌlti ˈɔːɡən ˈfeɪljər/), also known as multiple organ dysfunction syndrome (MODS), is a severe, potentially life-threatening condition where two or more organs in the body fail to function properly.

Etymology

The term "multi-organ failure" is derived from the Latin words "multus" meaning "many", "organum" meaning "instrument", and "fallere" meaning "to deceive or fail".

Definition

Multi-organ failure is a complex and challenging syndrome that occurs when the body's response to a severe illness or injury results in the dysfunction of two or more organ systems. This can include the heart, lungs, kidneys, liver, brain, and gastrointestinal tract.

Causes

Multi-organ failure can be caused by a variety of conditions, including severe infection, trauma, surgery, and certain chronic diseases. It is often a complication of sepsis, a life-threatening condition caused by the body's response to an infection.

Symptoms

Symptoms of multi-organ failure can vary widely depending on the organs affected, but may include shortness of breath, confusion, weakness, and swelling in the legs and ankles.

Treatment

Treatment for multi-organ failure typically involves addressing the underlying cause, such as treating the infection or managing the chronic disease. Supportive care, including ventilation for respiratory failure and dialysis for kidney failure, may also be necessary.

Prognosis

The prognosis for multi-organ failure depends on a variety of factors, including the patient's age, overall health, and the severity and number of organs affected. Despite advances in medical care, multi-organ failure remains a significant cause of mortality in critically ill patients.

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