Moxidectin

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Moxidectin

Moxidectin (pronounced: mox-i-dec-tin) is a parasiticide used for the prevention and control of various parasitic infestations in animals. It is derived from the actinomycete Streptomyces cyaneogriseus subsp. noncyanogenus.

Etymology

The term "Moxidectin" is derived from the words "moxie", meaning energy or pep, and "dectin", a type of protein found in fungi and bacteria that binds to carbohydrates. This is a reference to the drug's energetic action against parasites.

Usage

Moxidectin is used in veterinary medicine to treat a variety of parasitic infestations, including heartworm in dogs, gastrointestinal worms in livestock, and ectoparasites such as mites and lice. It is also used in humans to treat onchocerciasis, a disease caused by a type of roundworm.

Mechanism of Action

Moxidectin works by interfering with the parasite's nervous system, causing paralysis and death. It binds to the parasite's glutamate-gated chloride channels, disrupting the normal functioning of the nervous system.

Related Terms

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