Monogenic
Monogenic
Monogenic (/mɒnəˈdʒɛnɪk/; from the Greek words "mono", meaning "one", and "genic", meaning "originating from") refers to a condition or trait that is determined by a single gene. Monogenic conditions are inherited in recognizable patterns: autosomal dominant, autosomal recessive, and X-linked.
Etymology
The term "monogenic" is derived from two Greek words: "mono", which means "one", and "genic", which means "originating from". It is used to describe conditions or traits that are determined by a single gene.
Related Terms
- Gene: A unit of heredity which is transferred from a parent to offspring and is held to determine some characteristic of the offspring.
- Genetic Disorder: A genetic problem caused by one or more abnormalities in the genome.
- Autosomal Dominant: A pattern of inheritance characteristic of some genetic diseases. "Autosomal" means that the gene in question is located on one of the numbered, or non-sex, chromosomes.
- Autosomal Recessive: A type of inheritance pattern in which a child receives two copies of the defective gene, one from each parent.
- X-linked: A mode of genetic inheritance by which a mutation in a gene on the X chromosome causes the phenotype to be expressed in males (who are necessarily hemizygous for the gene mutation because they have one X and one Y chromosome) and in females who are homozygous for the gene mutation.
See Also
External links
- Medical encyclopedia article on Monogenic
- Wikipedia's article - Monogenic
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