Miproxifene phosphate
Miproxifene Phosphate
Miproxifene Phosphate (pronunciation: mi-prox-i-fene fos-fate) is a pharmaceutical drug used in the treatment of breast cancer. It belongs to the class of Selective Estrogen Receptor Modulators (SERMs).
Etymology
The term 'Miproxifene' is derived from the chemical structure of the drug, which is a modification of the structure of tamoxifen, a well-known SERM. The 'Phosphate' part of the name refers to the phosphate salt form of the drug, which is used to improve its solubility and bioavailability.
Pharmacology
Miproxifene Phosphate works by binding to estrogen receptors in breast cancer cells, thereby blocking the effects of estrogen, a hormone that can promote the growth of breast cancer cells. This mechanism of action is similar to that of other SERMs, such as tamoxifen and raloxifene.
Clinical Use
Miproxifene Phosphate is used in the treatment of estrogen receptor-positive breast cancer, a type of breast cancer that is sensitive to estrogen. It may be used as an adjuvant therapy, which means it is used in addition to other treatments, such as surgery, radiation, and chemotherapy.
Side Effects
Like all drugs, Miproxifene Phosphate can cause side effects. Common side effects include hot flashes, nausea, and fatigue. More serious side effects can include blood clots and endometrial cancer.
Related Terms
External links
- Medical encyclopedia article on Miproxifene phosphate
- Wikipedia's article - Miproxifene phosphate
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