Microvasculature remodeling

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Microvasculature Remodeling

Microvasculature remodeling (pronunciation: /ˌmaɪ.kroʊ.væs.kjʊˈlæ.tʃər riːˈmɒd.əl.ɪŋ/) is a biological process that involves the structural alteration of the microvasculature, the smallest blood vessels in the body, including capillaries, arterioles, and venules. This process is crucial in various physiological and pathological conditions.

Etymology

The term "microvasculature remodeling" is derived from three words: "micro" (Greek: μικρός, mikrós, 'small'), "vasculature" (Latin: vasculum, 'small vessel'), and "remodeling" (from the verb "remodel", meaning to model again or differently).

Physiological Role

Microvasculature remodeling plays a significant role in the body's response to various physiological stimuli. It is involved in processes such as angiogenesis and vasculogenesis, which are essential for tissue growth and repair.

Pathological Role

In pathological conditions, abnormal microvasculature remodeling can lead to diseases such as hypertension, diabetes, and cancer. In these conditions, the remodeling process can result in the formation of dysfunctional blood vessels, contributing to disease progression.

Related Terms

  • Angiogenesis: The formation of new blood vessels from pre-existing ones.
  • Vasculogenesis: The formation of blood vessels in embryonic or fetal tissue.
  • Hypertension: A chronic medical condition in which the blood pressure in the arteries is persistently elevated.
  • Diabetes: A group of metabolic disorders characterized by a high blood sugar level over a prolonged period.
  • Cancer: A group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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