WikiMD is the world's largest medical encyclopedia with
13,592 pages, 4,139,081 edits & 37,811,477 views.
Metronidazole
Information about Metronidazole
Metronidazole is a nitroimidazole derivative bactericidal agent widely used in the treatment of many anaerobic and certain protozoan and parasitic infections.
Liver safety of Metronidazole
Metronidazole has been linked to rare instances of acute, clinically apparent liver injury.
Mechanism of action of Metronidazole
Metronidazole (met" roe nid' a zole) is a nitroimidazole antibiotic that is activated by reduction of its nitro group by susceptible organisms. The activated form of metronidazole is a highly reactive radical anion which targets and damages large protein molecules and DNA. Mammalian cells do not ordinarily activate metronidazole, which accounts for its lack of toxicity in humans.
FDA approval information for Metronidazole
Metronidazole was approved for use in the United States in 1963 and currently several million prescriptions are filled yearly.
Clinical use of Metronidazole
Metronidazole is indicated for treatment and prophylaxis of infections with susceptible anaerobic bacteria and protozoa.
Dosage and administration for Metronidazole
The recommended dosage is 500 to 750 mg taken orally three times daily for 5 to 10 days. Metronidazole is available alone in tablets of 250, 375, 500 and 750 mg as well as in combination with other medications, in multiple generic formulations and under several brand names including Flagyl, Metryl, Noritate, Pylera and Helida. Other formulations include injectable solutions, extended release tablets, suppositories, and topical creams.
Side effects of Metronidazole
The most common side effects include metallic taste, nausea, vomiting, abdominal discomfort and diarrhea.
Cost and Coupons - Metronidazole
- GoodRx compare cost & coupons for Metronidazole
- Find the lowest cost of Metronidazole
- Search for Coupons for Metronidazole
Reviews for Metronidazole
Learn more about Metronidazole
- Dailymed label info
- Scientific articles
- Drug portal Metronidazole
- toxicity info on Metronidazole
- FDA Metronidazole
Latest research - Metronidazole
External links
This WikiMD article Metronidazole is a stub. If you are familiar with the topic Metronidazole, you can help us. Paid editors welcome!
Metronidazole is part of WikiMD's free ^articles!
WikiMD is not a substitute for professional advice. By accessing and using WikiMD you agree to the terms of use.
Templates etc. when imported from Wikipedia, are licensed under CC BY-SA 3.0. See full disclaimers.
 Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP. Tele medicine available |
