Metrizamide
Metrizamide
Metrizamide (pronunciation: meh-tri-ZAH-mide) is a radiopaque agent used in medical imaging to enhance the visibility of certain structures or fluids within the body. It is often used in myelography, a type of radiographic examination that uses a contrast medium to detect pathology of the spinal cord, including the location of a spinal cord injury, cysts, and tumors.
Etymology
The term "Metrizamide" is derived from its chemical structure. It is a nonionic, water-soluble contrast medium, which was developed in the 1970s. The name is a combination of parts of its chemical name, 3-(acetyl-amino)-2,4,6-triiodo-5-methoxy-N,N'-bis(2,3-dihydroxypropyl)-isophthalamide.
Usage
Metrizamide is used in various types of diagnostic imaging procedures, including CT scans, angiography, and myelography. It is injected into the body where it absorbs or scatters radiation, allowing the targeted area to be distinguished from surrounding tissue.
Related Terms
- Radiopaque Agents: Substances used to allow visualization of certain structures in radiographic examinations.
- Myelography: A type of radiographic examination that uses a contrast medium to detect pathology of the spinal cord.
- Computed Tomography: An imaging procedure that uses special x-ray equipment to obtain cross-sectional pictures of the body.
- Angiography: A medical imaging technique used to visualize the inside of blood vessels and organs of the body.
Side Effects
Like all contrast media, Metrizamide can cause side effects, although not everybody gets them. These can range from mild reactions like a rash or itching to more serious reactions such as difficulty breathing or loss of consciousness.
Precautions
Patients with a known hypersensitivity to iodine or any of the other ingredients in Metrizamide should not be given this contrast medium. It should also be used with caution in patients with severe kidney disease, thyroid disorder, or a history of asthma or allergies.
External links
- Medical encyclopedia article on Metrizamide
- Wikipedia's article - Metrizamide
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