Meglitinide

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Meglitinide

Meglitinide (pronounced meh-gli-tin-ide) is a class of drugs used in the treatment of Type 2 diabetes.

Etymology

The term "Meglitinide" is derived from the chemical structure of the drug, which contains a meglitinide moiety.

Definition

Meglitinides are a class of oral antidiabetic drugs that stimulate insulin secretion from the pancreas. They are also known as "glinides" and are used in the management of Type 2 diabetes when diet and exercise alone does not result in good glycemic control.

Mechanism of Action

Meglitinides work by binding to an ATP-dependent potassium channel on the beta cell membrane of the pancreas. This leads to cell depolarization and subsequent insulin release.

Related Terms

  • Repaglinide: A meglitinide analog that is commonly used in the treatment of Type 2 diabetes.
  • Nateglinide: Another meglitinide analog used in the treatment of Type 2 diabetes.
  • Prandial glucose regulators: A class of drugs that includes meglitinides. They are taken shortly before meals to reduce postprandial hyperglycemia.

Side Effects

Common side effects of meglitinides include hypoglycemia, weight gain, and joint pain.

See Also

External links

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