Intravascular papillary endothelial hyperplasia
Intravascular Papillary Endothelial Hyperplasia (IPA: /ɪntrəˈvæskjʊlər pæpɪˈlɛri ɛnˌdoʊθiːliːəl haɪpərˈpleɪziə/) is a rare benign vascular lesion characterized by excessive proliferation of endothelial cells within a blood vessel. The term is derived from the Greek words endothelium (inner layer of cells), hyper (over), and plasia (formation).
Definition
Intravascular Papillary Endothelial Hyperplasia (IPEH) is a benign vascular lesion that is characterized by the excessive proliferation of endothelial cells within a blood vessel. It is also known as Masson's Tumor or Masson's Lesion.
Etiology
The exact cause of IPEH is unknown. However, it is believed to be associated with a reaction to injury or inflammation, particularly in the presence of a thrombus or blood clot.
Clinical Presentation
Patients with IPEH typically present with a slow-growing, painless mass. The lesion can occur anywhere in the body but is most commonly found in the skin and subcutaneous tissues of the head, neck, and upper extremities.
Diagnosis
Diagnosis of IPEH is typically made through histopathological examination of a biopsy specimen. The lesion is characterized by the presence of papillary structures with a central vascular core lined by proliferating endothelial cells.
Treatment
Treatment for IPEH typically involves surgical excision of the lesion. Recurrence is rare following complete excision.
See Also
External links
- Medical encyclopedia article on Intravascular papillary endothelial hyperplasia
- Wikipedia's article - Intravascular papillary endothelial hyperplasia
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