Marcellomycin
Marcellomycin
Marcellomycin (pronunciation: mar-cel-lo-my-cin) is a chemical compound that belongs to the class of antibiotics known as anthracyclines. It was first isolated in the 1970s from the bacterium Streptomyces marcellus.
Etymology
The term "Marcellomycin" is derived from the name of the bacterium Streptomyces marcellus, from which it was first isolated. The suffix "-mycin" is commonly used in the nomenclature of antibiotics, particularly those derived from Streptomyces species.
Pharmacology
Marcellomycin is known for its potent antineoplastic properties. It works by intercalating into DNA and inhibiting the enzyme topoisomerase II, which is crucial for DNA replication and transcription. This leads to DNA damage and cell death, making Marcellomycin effective against certain types of cancer.
Related Terms
- Anthracyclines: A class of antibiotics that includes Marcellomycin.
- Streptomyces: A genus of bacteria from which Marcellomycin is derived.
- Topoisomerase II: An enzyme inhibited by Marcellomycin.
- Antineoplastic: Refers to substances that inhibit or prevent the growth and spread of cancer cells.
See Also
External links
- Medical encyclopedia article on Marcellomycin
- Wikipedia's article - Marcellomycin
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