Machine perfusion

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Machine Perfusion

Machine perfusion (pronunciation: /məˈʃiːn pərˈfjuːʒən/) is a method used in organ transplantation to preserve donated organs by mimicking the body's natural functions.

Etymology

The term "machine perfusion" is derived from the English words "machine" and "perfusion". "Machine" comes from the Latin word "machina", which means a structure or device. "Perfusion" is derived from the Latin word "perfusio", meaning "to pour over or through".

Definition

Machine perfusion is a technique that maintains the viability of organs outside the body for an extended period. It does this by continuously supplying the organ with a specially formulated solution that mimics blood, providing necessary oxygen and nutrients.

Types of Machine Perfusion

There are two main types of machine perfusion: hypothermic machine perfusion and normothermic machine perfusion. Hypothermic machine perfusion involves cooling the organ to slow its metabolic rate, while normothermic machine perfusion keeps the organ at body temperature, allowing it to continue functioning as it would in the body.

Related Terms

  • Organ transplantation: The surgical operation in which a failing or damaged organ in the human body is removed and replaced with a new one from a donor.
  • Hypothermic machine perfusion: A type of machine perfusion that involves cooling the organ to slow its metabolic rate.
  • Normothermic machine perfusion: A type of machine perfusion that keeps the organ at body temperature, allowing it to continue functioning as it would in the body.

See Also

External links

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