Lymphocytic esophagitis

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Lymphocytic esophagitis (pronunciation: lim-foh-sy-tik eh-sof-uh-jai-tis) is a rare and relatively recently recognized condition characterized by an increased number of lymphocytes in the esophagus. The etymology of the term comes from the Greek words "lympho" meaning clear fluid, "cyte" meaning cell, "esophagus" meaning gullet, and "itis" meaning inflammation.

Definition

Lymphocytic esophagitis is a histologic entity characterized by high numbers of esophageal intraepithelial lymphocytes without significant granulocytosis. It is a condition that is not well understood and is currently under research for better understanding and treatment options.

Symptoms

The symptoms of lymphocytic esophagitis can vary, but often include dysphagia (difficulty swallowing), heartburn, and chest pain. Some patients may also experience nausea or vomiting.

Causes

The exact cause of lymphocytic esophagitis is unknown. However, it is thought to be related to immune system response. Some researchers believe it may be associated with other conditions such as celiac disease, eosinophilic esophagitis, or gastroesophageal reflux disease (GERD).

Diagnosis

Diagnosis of lymphocytic esophagitis is typically made through an endoscopy and biopsy of the esophagus. The presence of a high number of lymphocytes in the esophagus is the key diagnostic feature.

Treatment

Treatment for lymphocytic esophagitis is largely symptomatic. This may include dietary changes, medications to reduce stomach acid, and in some cases, corticosteroids.

See also

External links

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