Lymphocytic colitis

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Lymphocytic Colitis

Lymphocytic colitis (pronunciation: lim-foh-SIT-ik koh-LY-tis) is a type of inflammatory bowel disease that affects the colon. It is characterized by chronic, non-bloody diarrhea and inflammation of the colon's innermost lining, the epithelium.

Etymology

The term "lymphocytic colitis" is derived from the words "lymphocyte," a type of white blood cell, and "colitis," which refers to inflammation of the colon. The condition is so named because it is characterized by an increase in lymphocytes in the colon lining.

Symptoms

The primary symptom of lymphocytic colitis is chronic, non-bloody diarrhea. Other symptoms may include abdominal pain, nausea, and weight loss. Some patients may also experience fatigue and dehydration due to frequent bowel movements.

Causes

The exact cause of lymphocytic colitis is unknown. However, it is believed to be associated with autoimmune disorders, in which the body's immune system attacks its own cells. Other potential triggers include certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), and infections.

Diagnosis

Diagnosis of lymphocytic colitis is typically made through a colonoscopy or sigmoidoscopy, during which a small sample of colon tissue is taken for examination under a microscope. The presence of increased lymphocytes in the colon lining confirms the diagnosis.

Treatment

Treatment for lymphocytic colitis aims to alleviate symptoms and may include dietary changes, medication, or in severe cases, surgery. Medications used to treat the condition include anti-inflammatory drugs, immunosuppressants, and corticosteroids.

Related Terms

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