Lupus erythematosus panniculitis

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Lupus erythematosus panniculitis

Lupus erythematosus panniculitis (pronunciation: loo-pus er-i-the-ma-toe-sus pan-i-cu-li-tis), also known as lupus profundus, is a rare form of chronic cutaneous lupus erythematosus that primarily affects the subcutaneous adipose tissue.

Etymology

The term 'Lupus erythematosus panniculitis' is derived from the Latin word 'lupus', meaning 'wolf', 'erythematosus', meaning 'red', and 'panniculitis', meaning 'inflammation of the fatty layer of the skin'. The term 'lupus' was used due to the wolf-like facial rash that is often associated with systemic lupus erythematosus.

Definition

Lupus erythematosus panniculitis is characterized by inflammation and degeneration of the subcutaneous fat. It can occur independently or in association with systemic or discoid lupus erythematosus. The condition is more common in women than in men and usually appears in the third to fifth decade of life.

Symptoms

The main symptom of lupus erythematosus panniculitis is the presence of deep-seated, tender nodules or plaques in the skin, most commonly on the face, scalp, upper arms, chest, and thighs. Other symptoms may include fatigue, joint pain, and fever.

Diagnosis

Diagnosis of lupus erythematosus panniculitis is based on clinical features, histopathological examination of a skin biopsy, and sometimes immunological tests.

Treatment

Treatment options for lupus erythematosus panniculitis include corticosteroids, antimalarial drugs, and immunosuppressive drugs. In severe cases, surgical intervention may be necessary.

Related Terms

External links

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