Limb bud

From WikiMD.org
Jump to navigation Jump to search

Limb Bud

Limb bud (/lɪm bʌd/), from the Latin limbus meaning edge or border, and the Old English budde meaning bud or shoot, is a structure formed in the embryonic stage of an organism which develops into a limb.

Definition

A limb bud is an outgrowth that appears in vertebrates on the ventrolateral body wall during embryogenesis. These buds consist of mesoderm covered by ectoderm, and they later develop into the limbs of the organism.

Development

The development of the limb bud is a complex process that involves a series of genetic and molecular interactions. The Apical Ectodermal Ridge (AER) and the Zone of Polarizing Activity (ZPA) are two critical regions in the limb bud that play a significant role in its development.

Related Terms

  • Apical Ectodermal Ridge (AER): A thickened area of ectoderm at the distal end of a limb bud that stimulates growth and elongation of the limb bud.
  • Zone of Polarizing Activity (ZPA): A region in the posterior part of the limb bud that secretes signals to guide the development of the anterior-posterior axis of the limb.
  • Mesoderm: One of the three primary germ layers in the very early embryo. The mesoderm is the middle layer. The other two layers are the ectoderm (outside layer) and endoderm (inside layer).
  • Ectoderm: The outermost layer of cells or tissue of an embryo in early development, or the parts derived from this, which include the epidermis, nerve tissue, and nephridia.

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski