Koeppe's nodules

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Koeppe's Nodules

Koeppe's nodules (pronounced: kuh-PEEZ noh-dyoolz) are small, round, inflammatory nodules found at the pupillary margin of the iris in the eye. They are named after the German ophthalmologist Leopold Koeppe, who first described them.

Etymology

The term "Koeppe's nodules" is derived from the name of the German ophthalmologist Leopold Koeppe, who first described these nodules in the early 20th century. The term "nodule" comes from the Latin "nodulus", meaning a small knot, which describes the appearance of these formations.

Description

Koeppe's nodules are typically associated with uveitis, an inflammation of the uvea, the middle layer of the eye. They are often seen in conditions such as juvenile idiopathic arthritis (JIA), Fuchs' heterochromic iridocyclitis, and sarcoidosis. The nodules themselves are collections of inflammatory cells and are usually visible to the naked eye.

Diagnosis

Diagnosis of Koeppe's nodules is typically made through a clinical examination of the eye, often using a slit lamp to visualize the nodules. They are usually associated with other signs of inflammation in the eye, such as redness, pain, and sensitivity to light.

Treatment

Treatment for Koeppe's nodules typically involves addressing the underlying cause of the inflammation. This may involve the use of anti-inflammatory medications, such as corticosteroids, or treatment for the specific condition causing the inflammation, such as medication for JIA or sarcoidosis.

Related Terms

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