Kikuchi disease
Kikuchi Disease
Kikuchi Disease (pronounced: kee-koo-chee disease), also known as Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis, is a rare, benign condition that affects the lymph nodes.
Etymology
The disease is named after the Japanese pathologists, Dr. Masahiro Kikuchi and Dr. Y. Fujimoto, who independently discovered the condition in 1972.
Definition
Kikuchi Disease is a self-limiting illness characterized by lymphadenopathy (swelling of the lymph nodes), particularly in the cervical region. It is often accompanied by mild fever, night sweats, and weight loss. The disease primarily affects young adults and is more common in females and people of Asian descent.
Symptoms
The most common symptom of Kikuchi Disease is painful lymphadenopathy, particularly in the neck. Other symptoms may include:
Diagnosis
Diagnosis of Kikuchi Disease is typically made through a biopsy of an affected lymph node. The biopsy often shows necrotizing histiocytic lymphadenitis, which is characteristic of the disease.
Treatment
There is no specific treatment for Kikuchi Disease as it is self-limiting and usually resolves on its own within one to four months. Treatment is typically aimed at managing symptoms and may include non-steroidal anti-inflammatory drugs (NSAIDs) for pain and fever, and corticosteroids in severe cases.
Prognosis
The prognosis for Kikuchi Disease is generally good, with most patients experiencing a full recovery. However, relapses can occur in some cases.
See Also
External links
- Medical encyclopedia article on Kikuchi disease
- Wikipedia's article - Kikuchi disease
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