JPS

JPS
Term	JPS
Short definition	JPS - A rare, inherited condition in which multiple abnormal growths called juvenile polyps form in the gastrointestinal tract, usually before the age of 20. To be diagnosed with JPS, an individual must have one or more of the following characteristics: (1) more than five juvenile polyps in the colon or rectum; (2) juvenile polyps in other parts of the gastrointestinal tract, including the stomach or small intestine; (3) any number of juvenile polyps and a family history of JPS.
Type	Cancer terms
Specialty	Oncology
Language	English
Source	NCI
Comments

JPS - A rare, inherited condition in which multiple abnormal growths called juvenile polyps form in the gastrointestinal tract, usually before the age of 20. To be diagnosed with JPS, an individual must have one or more of the following characteristics: (1) more than five juvenile polyps in the colon or rectum; (2) juvenile polyps in other parts of the gastrointestinal tract, including the stomach or small intestine; (3) any number of juvenile polyps and a family history of JPS. Other signs and symptoms include diarrhea, gastrointestinal bleeding, abdominal pain, anemia, extra fingers and toes, and abnormalities of the heart, brain, palate, intestines, urinary tract, and genitals. People with JPS also have an increased risk of colon, stomach, small bowel, and pancreatic cancers. JPS is caused by mutations (changes) in the SMAD4 or BMPR1A genes, which are inherited in an autosomal dominant manner. It's a kind of hereditary cancer syndrome. Also called juvenile polyposis syndrome

External links

• Medical encyclopedia article on JPS
• Wikipedia's article - JPS

This WikiMD dictionary article is a stub. You can help make it a full article.

---

Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski