Isolated lung perfusion

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Isolated Lung Perfusion (Pronunciation: Isolated - [ˈīsəˌlādəd], Lung - [ləNG], Perfusion - [pərˈfyo͞oZHən]) is a medical procedure that allows for the targeted delivery of high-dose chemotherapy to the lung, while minimizing systemic exposure and toxicity.

Etymology

The term "Isolated Lung Perfusion" is derived from the English language. "Isolated" comes from the Latin word "insulatus" meaning "made into an island", "Lung" is from the Old English "lungen" and "Perfusion" is from the Latin "perfundere" meaning "to pour over".

Procedure

The Isolated Lung Perfusion procedure involves the surgical isolation of the lung's blood supply from the rest of the body's circulation. This is achieved by clamping the pulmonary artery and pulmonary vein, and then connecting the lung to a heart-lung machine. The lung is then perfused with a solution containing high-dose chemotherapy drugs. The procedure allows for the targeted treatment of lung tumors, while minimizing the exposure of the rest of the body to the chemotherapy drugs.

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