Isatin
Isatin
Isatin (pronounced as /ˈaɪsətɪn/) is a heterocyclic compound that is an organic compound with the formula C8H5NO2.
Etymology
The term "Isatin" is derived from the combination of the words "indigo" and "satin", referring to its discovery in the processing of the indigo plant and its satiny texture.
Description
Isatin is an indole derivative, specifically an oxindole, which is a type of organic compound. It is a solid substance that is orange in color. It is a lactam and an oxo heterocycle. It is a conjugate acid of an isatin(1-). Isatin is a derivative of indole with a carbonyl group at position 2 and an oxo group at position 3. It is produced by many organisms, and can be derived from indigo dye.
Synthesis
Isatin can be synthesized from indigo dye by Baeyer's method, which involves oxidation of indigo dye with nitric acid and chromic acid. It can also be synthesized from aniline via the Sandmeyer reaction.
Uses
Isatin is used as a reagent in the synthesis of various pharmaceutical compounds. It is also used in the synthesis of dyes and in the preparation of indigo dye.
Related Terms
External links
- Medical encyclopedia article on Isatin
- Wikipedia's article - Isatin
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