Insertion mutation

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Insertion Mutation

An Insertion Mutation (pronunciation: in-sur-shun myu-tey-shun) is a type of genetic mutation where one or more nucleotide pairs are added to a gene sequence.

Etymology

The term "Insertion Mutation" is derived from the English words "insertion", meaning the action of inserting something, and "mutation", which refers to the changing of the structure of a gene.

Definition

In the context of genetics, an Insertion Mutation refers to the addition of one or more nucleotide pairs into a DNA sequence. This can lead to significant changes in the protein produced by the gene, as the insertion can shift the reading frame of the gene, a phenomenon known as a frameshift mutation.

Related Terms

  • Frameshift Mutation: A type of mutation caused by insertions or deletions of a number of nucleotides in a DNA sequence that is not divisible by three.
  • Point Mutation: A mutation affecting only one or very few nucleotides in a gene sequence.
  • Deletion Mutation: A mutation in which a part of a chromosome or a sequence of DNA is left out during DNA replication.
  • Duplication Mutation: A mutation that involves duplication of a region of DNA on a chromosome.
  • Nonsense Mutation: A mutation in a sequence of DNA that results in a premature stop codon, or a nonsense codon in the transcribed mRNA, and possibly a truncated, and often nonfunctional protein product.

See Also

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