Inotropes
Inotropes
Inotropes (pronounced: /ˈaɪnəˌtroʊp/) are a group of medicines that alter the force or energy of muscular contractions. Negatively inotropic agents weaken the force of muscular contractions. Positively inotropic agents increase the strength of muscular contraction.
The term inotrope comes from the Greek words ino meaning fibre and tropos meaning a turning. It was first used in the medical field in the 1960s.
Types of Inotropes
Inotropes can be classified into two main types:
- Positive inotropes: These increase the force of the heart's contractions, allowing it to pump more blood. Examples include dobutamine and digoxin.
- Negative inotropes: These decrease the force of the heart's contractions and slow the heart rate. Examples include beta blockers such as metoprolol.
Uses of Inotropes
Inotropes are used in the treatment of various heart conditions such as heart failure, cardiogenic shock, and during cardiac surgery. They help to improve heart function and increase blood flow.
Side Effects of Inotropes
Like all medications, inotropes can have side effects. These can include arrhythmias, hypertension, and palpitations. It's important for patients to discuss potential side effects with their healthcare provider.
Related Terms
- Chronotropes: These are drugs that change the heart rate by affecting the electrical impulses in the heart's conduction system.
- Vasopressors: These are medicines that constrict (narrow) the blood vessels, increasing blood pressure.
External links
- Medical encyclopedia article on Inotropes
- Wikipedia's article - Inotropes
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