Indometacin farnesil
Indometacin Farnesil
Indometacin Farnesil (pronounced as in-doh-meth-uh-sin far-ne-sil) is a prodrug of the non-steroidal anti-inflammatory drug (NSAID) Indometacin.
Etymology
The term "Indometacin" is derived from the words 'indole', 'acetic acid', and 'amine', which are the key components of its chemical structure. The term "Farnesil" refers to the farnesyl group, a type of lipid, which is attached to the indometacin molecule to form the prodrug.
Pharmacology
Indometacin Farnesil is metabolized in the body to release Indometacin, which exerts its therapeutic effects by inhibiting the production of prostaglandins, substances that cause inflammation and pain in the body. The farnesyl group in Indometacin Farnesil enhances the drug's lipophilicity, allowing it to be better absorbed and distributed in the body.
Medical Uses
Indometacin Farnesil is used in the treatment of various conditions associated with pain and inflammation, such as Rheumatoid Arthritis, Osteoarthritis, and Gout. It is also used to alleviate pain caused by various other conditions, such as Bursitis and Tendinitis.
Side Effects
Like other NSAIDs, Indometacin Farnesil can cause various side effects, including gastrointestinal problems, such as Peptic Ulcer and Gastrointestinal Bleeding, and cardiovascular problems, such as Hypertension and Heart Failure. It can also cause Renal Impairment in some patients.
Related Terms
- Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
- Prostaglandins
- Prodrug
- Pharmacokinetics
- Pharmacodynamics
External links
- Medical encyclopedia article on Indometacin farnesil
- Wikipedia's article - Indometacin farnesil
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