In-situ

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In-situ

In-situ (pronounced in-see-too) is a Latin phrase that translates directly to "in position" or "in its original place". It is often used in various scientific and medical contexts to describe something that is in its natural, original, or appropriate position or place.

Etymology

The term "in-situ" originates from Latin, where "in" translates to "in" and "situ" translates to "place" or "position". It has been adopted into English and is used across various fields including geology, astronomy, archaeology, and medicine.

Medical Usage

In the field of medicine, "in-situ" is used to describe a condition where abnormal cells are present but have not spread to neighboring tissue. For example, cancer in-situ, or carcinoma in-situ, is a cancer that is still confined to the cells where it started.

In-situ can also refer to medical procedures that are performed "in place". For example, in-situ biopsy is a procedure where a sample of tissue is taken from the exact place where it is found in the body for further examination.

Related Terms

  • Carcinoma in-situ: A term used to describe cancer that has stayed in the place where it began and has not spread to neighboring tissues.
  • Biopsy: A procedure that removes cells or tissues for examination.
  • In-situ hybridization: A type of hybridization that uses a labeled complementary DNA, RNA or modified nucleic acids strand to localize a specific DNA or RNA sequence in a portion or section of tissue.

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