Immunoreactive trypsinogen
Immunoreactive Trypsinogen (pronunciation: im·mu·no·re·ac·tive tryp·sin·o·gen) is a protein that is produced in the pancreas and released into the bloodstream. It is often used as a marker in newborn screening tests for Cystic Fibrosis.
Etymology
The term "Immunoreactive Trypsinogen" is derived from three words: "Immuno-" which refers to the immune system, "-reactive" which indicates a response or reaction, and "Trypsinogen" which is a type of protein produced in the pancreas.
Function
Immunoreactive Trypsinogen is a precursor to the enzyme Trypsin. Trypsin is responsible for the digestion of proteins in the small intestine. When the pancreas is functioning normally, small amounts of trypsinogen are released into the bloodstream. However, in conditions such as Cystic Fibrosis, the levels of immunoreactive trypsinogen in the blood can be significantly higher.
Clinical Significance
Immunoreactive Trypsinogen is used in newborn screening tests for Cystic Fibrosis. A high level of immunoreactive trypsinogen in a newborn's blood can be an early indicator of this disease. However, further tests are needed to confirm the diagnosis.
Related Terms
- Cystic Fibrosis
- Trypsin
- Pancreas
- Protein
- Enzyme
- Digestion
- Small Intestine
- Bloodstream
- Newborn Screening
External links
- Medical encyclopedia article on Immunoreactive trypsinogen
- Wikipedia's article - Immunoreactive trypsinogen
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