Immune reconstitution inflammatory syndrome

Immune Reconstitution Inflammatory Syndrome (IRIS, /ˈaɪrɪs/) is a condition seen in some cases of AIDS or HIV treatment.

Etymology

The term "Immune Reconstitution Inflammatory Syndrome" was first used in 1998 to describe a collection of inflammatory disorders associated with paradoxical worsening of pre-existing infectious processes following the initiation of antiretroviral therapy (ART) in HIV-infected individuals.

Definition

Immune Reconstitution Inflammatory Syndrome is a condition that can occur when a person starts antiretroviral therapy for HIV infection, and their immune system responds to previously acquired opportunistic infections with an overwhelming inflammatory response that paradoxically makes the symptoms of infection worse.

Related Terms

• Opportunistic infection
• Antiretroviral therapy
• Inflammation
• HIV
• AIDS

Symptoms

Symptoms of IRIS can vary widely depending on the type of opportunistic infection involved, but they generally include fever, worsening of the signs and symptoms of the opportunistic infection, and sometimes new signs and symptoms of the opportunistic infection.

Treatment

Treatment of IRIS is generally supportive, and may include continuation of antiretroviral therapy, treatment of the opportunistic infection, and sometimes anti-inflammatory medication.

See Also

• Opportunistic infection
• Antiretroviral therapy
• Inflammation
• HIV
• AIDS

External links

• Medical encyclopedia article on Immune reconstitution inflammatory syndrome
• Wikipedia's article - Immune reconstitution inflammatory syndrome

This WikiMD dictionary article is a stub. You can help make it a full article.

---

Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski