Ibogaine

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Ibogaine (pronounced /ˈaɪbəˌɡeɪn/) is a naturally occurring psychoactive substance found in plants in the Apocynaceae family such as Tabernanthe iboga, Voacanga africana, and Tabernaemontana undulata. It is a psychedelic with dissociative properties.

Etymology

The term "Ibogaine" is derived from the plant name "Tabernanthe iboga", which is one of the primary sources of the substance. The "-ine" suffix is commonly used in chemistry to denote a particular group or class of compounds.

Pharmacology

Ibogaine is classified as a psychedelic, but it also has significant dissociative properties. Its psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor. However, the role of these interactions and how they result in the psychedelic experience continues to remain an object of scientific elucidation.

Medical Use

Ibogaine has been used in some cultures as a traditional medicine and spiritual sacrament. In the Western world, it has been studied for its potential use in treating opioid addiction. Some research suggests that it may help with drug addiction withdrawal symptoms, but more research is needed.

Safety

Ibogaine is not without risks. It has been associated with potentially life-threatening heart complications, and there is a lack of data about its long-term effects. It is currently a Schedule I controlled substance in the United States, and it is also illegal in several other countries.

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