Hydroxyprogesterone acetate
Hydroxyprogesterone Acetate
Hydroxyprogesterone Acetate (pronounced as hy-drox-ee-proh-JES-ter-ohn a-SEH-tate) is a progestin medication which is used in the treatment of gynecological disorders and as a part of hormone replacement therapy.
Etymology
The term 'Hydroxyprogesterone' is derived from the words 'hydroxy', which refers to the presence of a hydroxyl group, and 'progesterone', a type of female hormone. 'Acetate' refers to the presence of an acetate group in the chemical structure of the compound.
Usage
Hydroxyprogesterone Acetate is used in the treatment of various gynecological disorders such as endometriosis, uterine fibroids, and menopausal symptoms. It is also used as a part of hormone replacement therapy in postmenopausal women.
Mechanism of Action
Hydroxyprogesterone Acetate works by binding to and activating the progesterone receptor, thereby exerting its progestogenic effects. It inhibits the growth of the lining of the uterus and is used to prevent endometrial hyperplasia in women who are receiving estrogen replacement therapy.
Side Effects
Common side effects of Hydroxyprogesterone Acetate include nausea, bloating, breast tenderness, and headache. Serious side effects may include blood clots, stroke, and heart attack.
Related Terms
- Progestin
- Gynecological disorders
- Hormone replacement therapy
- Endometriosis
- Uterine fibroids
- Menopausal symptoms
- Progesterone receptor
- Endometrial hyperplasia
- Nausea
- Bloating
- Breast tenderness
- Headache
- Blood clots
- Stroke
- Heart attack
External links
- Medical encyclopedia article on Hydroxyprogesterone acetate
- Wikipedia's article - Hydroxyprogesterone acetate
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