Hydralazine hydrochloride

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Hydralazine hydrochloride

Hydralazine hydrochloride (pronunciation: hye-DRAL-a-zeen HYE-droe-KLOR-ide) is a medication primarily used in the treatment of high blood pressure. It belongs to a class of drugs known as vasodilators, which work by relaxing and widening blood vessels to allow blood to flow more easily.

Etymology

The term "Hydralazine" is derived from the chemical structure of the drug, which includes a hydrazine functional group. The "hydrochloride" part of the name refers to the hydrochloride salt form in which the drug is often administered.

Pharmacology

Hydralazine hydrochloride acts directly on vascular smooth muscle to cause muscle relaxation, leading to vasodilation, and drop in blood pressure. It is thought to interfere with calcium ion release in the muscles, preventing the contractions that would narrow the blood vessels.

Usage

Hydralazine hydrochloride is used alone or with other medications to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It may also be used with other medications to treat heart failure.

Side Effects

Common side effects of Hydralazine hydrochloride include headache, loss of appetite, nausea, vomiting, diarrhea, fast heart rate, palpitations, and sweating. It is important to consult a healthcare provider if any of these side effects persist or worsen.

Related Terms

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