Hybridoma

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Hybridoma

Hybridoma (/haɪˈbrɪdəmə/) is a cell hybrid resulting from the fusion of a B cell and a myeloma cell. The term is derived from the words "hybrid" and "myeloma".

Etymology

The term "hybridoma" is a portmanteau of "hybrid" and "myeloma". "Hybrid" is derived from the Latin hybrida, meaning the offspring of two different species, and "myeloma" is derived from the Greek words myelos (marrow) and -oma (tumor).

Function

Hybridomas are used in the production of monoclonal antibodies. The B cell provides the ability to produce a specific antibody, while the myeloma cell provides longevity and the ability to proliferate indefinitely. This combination allows for the production of large quantities of a single type of antibody.

Related Terms

  • Monoclonal Antibodies: Antibodies that are identical because they were produced by one type of immune cell, all clones of a single parent cell.
  • B Cell: A type of white blood cell of the lymphocyte subtype.
  • Myeloma Cell: A cancer cell that originates in the plasma cells in the bone marrow.
  • Antibody: A blood protein produced in response to and counteracting a specific antigen.

See Also

External links

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