Hepatocellular adenoma
Hepatocellular adenoma (pronunciation: heh-puh-toh-sel-yuh-luhr ad-uh-noh-muh) is a rare, benign liver tumor that primarily affects women of childbearing age.
Etymology
The term "hepatocellular" is derived from the Greek words "hepar" (liver) and "kýtos" (cell), while "adenoma" comes from the Greek "aden" (gland) and "-oma" (tumor).
Definition
Hepatocellular adenoma is a benign neoplasm that originates from the hepatocyte, the main cell type in the liver. It is often associated with the use of oral contraceptive pills and other conditions that increase the level of estrogen in the body.
Symptoms
Most patients with hepatocellular adenoma are asymptomatic. However, some may experience abdominal pain, a palpable mass, or have an incidental finding on imaging studies. In rare cases, the tumor can rupture, leading to life-threatening hemorrhage.
Diagnosis
Diagnosis of hepatocellular adenoma can be challenging due to its rarity and nonspecific symptoms. It is often discovered incidentally during imaging studies for other conditions. Ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) can be used to identify and characterize the lesion. A biopsy may be necessary to confirm the diagnosis.
Treatment
The treatment for hepatocellular adenoma depends on the size of the tumor and the presence of symptoms. Small, asymptomatic tumors may be managed with regular monitoring and discontinuation of estrogen therapy. Larger tumors or those causing symptoms may require surgical resection.
Prognosis
The prognosis for hepatocellular adenoma is generally good, especially when the tumor is small and asymptomatic. However, there is a risk of malignant transformation into hepatocellular carcinoma, especially in tumors larger than 5 cm.
See also
External links
- Medical encyclopedia article on Hepatocellular adenoma
- Wikipedia's article - Hepatocellular adenoma
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