H1 antagonist

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H1 Antagonist

H1 antagonist (pronunciation: /eɪtʃ wʌn æntæɡənɪst/) refers to a type of drug that inhibits the action of histamine at the H1 receptor. These drugs are primarily used to treat allergies and hay fever.

Etymology

The term "H1 antagonist" is derived from the name of the receptor it acts upon, the H1 receptor, and the term "antagonist", which in pharmacology refers to a substance that interferes with or inhibits the physiological action of another.

Related Terms

  • Histamine: A compound that is released by cells in response to injury and in allergic and inflammatory reactions, causing contraction of smooth muscle and dilation of capillaries.
  • H1 receptor: A type of receptor found in smooth muscle and endothelial cells among other locations in the body. It is stimulated by histamine.
  • Antihistamine: A drug or other compound that inhibits the physiological effects of histamine, used especially in the treatment of allergies.
  • Allergies: A damaging immune response by the body to a substance, especially pollen, fur, a particular food, or dust, to which it has become hypersensitive.
  • Hay fever: A common allergic condition that can cause a wide range of symptoms, including sneezing, a runny nose and itchy eyes, usually as a reaction to pollen.

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