Granulomatosis
Granulomatosis
Granulomatosis (pronounced: gran-yuh-loh-muh-TOH-sis) is a medical term referring to a type of inflammation that occurs in certain diseases. It is characterized by the formation of granulomas, which are small nodules of inflammatory cells.
Etymology
The term "granulomatosis" is derived from the Latin word "granulum," which means "small grain," and the Greek suffix "-osis," which denotes a condition or process. The term is used to describe the grain-like nodules that form in this type of inflammation.
Related Terms
- Granuloma: A granuloma is a small area of inflammation due to tissue injury. It is characterized by the accumulation of macrophages, T lymphocytes, and epithelioid cells.
- Inflammation: Inflammation is a process by which the body's white blood cells and substances they produce protect us from infection with foreign organisms, such as bacteria and viruses.
- Macrophages: Macrophages are a type of white blood cell that engulfs and digests cellular debris, foreign substances, microbes, and cancer cells in a process called phagocytosis.
- T lymphocytes: T lymphocytes, or T cells, are a type of white blood cell that play a central role in cell-mediated immunity.
- Epithelioid cells: Epithelioid cells are a type of cell found in certain types of immune responses and in certain forms of granulomatous inflammation.
Types of Granulomatosis
There are several types of granulomatosis, including:
- Wegener's Granulomatosis: Also known as Granulomatosis with polyangiitis, it is a rare disease that causes the inflammation of the blood vessels, which can restrict blood flow and damage organs.
- Churg-Strauss Syndrome: Also known as Eosinophilic Granulomatosis with Polyangiitis, it is a disorder marked by blood vessel inflammation which can cause damage to organs and tissues.
- Sarcoidosis: This is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomas.
External links
- Medical encyclopedia article on Granulomatosis
- Wikipedia's article - Granulomatosis
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