Graft rejection
Graft Rejection
Graft rejection (pronunciation: /ɡræft rɪˈdʒɛkʃən/) is a complex process that occurs when the recipient's immune system recognizes the transplanted organ or tissue as foreign and mounts an immune response against it, leading to the destruction of the graft.
Etymology
The term "graft rejection" is derived from the English words "graft" (from Old Norse 'grǫftr', meaning 'dig') and "rejection" (from Latin 'reicere', meaning 'to throw back'). In the context of transplantation, a graft refers to the organ or tissue that is transplanted.
Types of Graft Rejection
There are three main types of graft rejection: hyperacute, acute, and chronic.
- Hyperacute rejection occurs within minutes to hours after transplantation. It is caused by pre-existing antibodies in the recipient that react with antigens on the graft.
- Acute rejection typically occurs days to weeks after transplantation. It is mediated by T cells that recognize foreign antigens on the graft.
- Chronic rejection occurs months to years after transplantation. It is characterized by gradual loss of graft function and is often associated with fibrosis and scarring.
Related Terms
- Graft - An organ or tissue that is transplanted.
- Transplantation - The process of transferring an organ or tissue from one person (the donor) to another (the recipient).
- Immune response - The body's defensive reaction to foreign substances, including transplanted organs or tissues.
- Antigen - A substance that triggers an immune response.
- Antibody - A protein produced by the immune system that recognizes and binds to specific antigens.
- T cell - A type of white blood cell that plays a key role in the immune response, including graft rejection.
See Also
External links
- Medical encyclopedia article on Graft rejection
- Wikipedia's article - Graft rejection
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski