Germinal matrix
Germinal Matrix
The Germinal Matrix (pronunciation: /ˈdʒɜːrmɪnəl ˈmeɪtrɪks/) is a highly cellular and highly vascularized region in the brain from which cells migrate during brain development.
Etymology
The term "Germinal Matrix" is derived from the Latin words "germen" meaning "sprout" and "matrix" meaning "womb". This term accurately describes the role of the germinal matrix as the 'birthplace' of neurons and glial cells in the developing brain.
Function
The Germinal Matrix is responsible for the production of neurons and glial cells during the prenatal period. These cells then migrate to their final destinations in the brain. The germinal matrix is most active during the second trimester of pregnancy and gradually regresses thereafter, disappearing completely by term.
Related Terms
- Neuron: A specialized cell transmitting nerve impulses; a nerve cell.
- Glial Cells: Non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain and peripheral nervous system.
- Prenatal Development: The process in which an embryo or fetus (or foetus) gestates during pregnancy, from fertilization until birth.
- Second Trimester: The middle period of pregnancy, extending from the 13th to the 28th week.
Pathology
Abnormalities in the germinal matrix can lead to a number of neurological disorders, including Germinal Matrix Hemorrhage, a condition common in premature infants where bleeding occurs in the subventricular zone.
External links
- Medical encyclopedia article on Germinal matrix
- Wikipedia's article - Germinal matrix
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