GeneXpert MTB/RIF
GeneXpert MTB/RIF
GeneXpert MTB/RIF (pronounced: jee-nee-expert em-tee-bee/arr-eye-eff) is a molecular testing method that identifies the Mycobacterium tuberculosis bacteria and resistance to the antibiotic rifampicin.
Etymology
The term "GeneXpert" is a combination of "gene," referring to the genetic material that the test analyzes, and "expert," indicating the system's advanced capabilities. "MTB" stands for Mycobacterium tuberculosis, the bacterium that causes tuberculosis, and "RIF" stands for rifampicin, an antibiotic used in the treatment of tuberculosis.
Description
The GeneXpert MTB/RIF test is a rapid diagnostic test that uses nucleic acid amplification technology to detect Mycobacterium tuberculosis complex (MTBC) and rifampicin resistance, both of which are indicative of multidrug-resistant tuberculosis (MDR-TB). The test is automated and can provide results within two hours.
Related Terms
- Mycobacterium tuberculosis: The bacterium that causes tuberculosis.
- Rifampicin: An antibiotic used in the treatment of tuberculosis.
- Multidrug-resistant tuberculosis (MDR-TB): A form of tuberculosis that is resistant to at least two of the main first-line drugs.
- Nucleic acid amplification: A laboratory technique used to make multiple copies of a specific genetic sequence.
See Also
External links
- Medical encyclopedia article on GeneXpert MTB/RIF
- Wikipedia's article - GeneXpert MTB/RIF
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