Gardner's syndrome

From WikiMD.org
Jump to navigation Jump to search

Gardner's Syndrome

Gardner's syndrome (pronounced: gahr-dnerz sin-drohm) is a rare genetic disorder. It is a variant of a condition known as familial adenomatous polyposis (FAP).

Etymology

The syndrome is named after Eldon J. Gardner, an American geneticist who first described the condition in 1951.

Definition

Gardner's syndrome is characterized by the presence of multiple polyps in the colon together with tumors outside the colon. These extra-colonic tumors may include osteomas (benign bone tumors), desmoid tumors, and other benign or malignant tumors.

Symptoms

Symptoms of Gardner's syndrome may include abdominal pain, diarrhea, blood in the stool, and weight loss. The polyps in the colon can become cancerous if not removed.

Diagnosis

Diagnosis of Gardner's syndrome can be confirmed through genetic testing, as the condition is caused by mutations in the APC gene. Other diagnostic methods may include colonoscopy or sigmoidoscopy to detect polyps in the colon.

Treatment

Treatment for Gardner's syndrome typically involves surgery to remove the polyps and prevent colon cancer. Other treatments may be necessary depending on the types and locations of extra-colonic tumors.

Related Terms

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski